President Donald Trump’s push for major cuts to research funding in the US are fueling even closer scientific ties between our two countries. Preliminary talks have begun between the US National Science Foundation and research funders in Canada to kickstart new research collaborations in quantum computing, the brain, biodiversity and the Arctic. Recent meetings held in both Ottawa and Washington are expected, as a first step, to result in a Dear Colleague letter from the NSF encouraging its researchers to identify opportunities for joint projects the rapidly evolving field of brain research.