A highly anticipated report says heritable genome editing, using tools like CRISPR to create edits that can be passed down to future generations, is not yet safe enough for clinical use. But it also provides specific guidance on how nations should prepare for the eventual use of CRISPR or other gene editing tools, defining a translational pathway from research to the clinic.
Topic: Human genome editing
The WHO has launched a global registry to track research on human genome editing—the first concrete recommendation of an advisory committee charged with determining what an effective oversight and governance framework should look like in the CRISPR era. At the same time, medical and scientific societies in other nations are grappling with the unprecedented ethical and scientific implications of altering the human genome in future generations.